Stool examination help to find a variety of cancers
CHICAGO (Reuters) - U.S. researchers said Tuesday: It is perhaps only
one stool sample can detect cancer and many other digestive tract
(including stomach, pancreas, biliary tract, esophagus) cancer.
A fall off the surface of cancer cells by detecting the genetic
material of the new method can be found in nearly 70% of all digestive
tract cancers.
Mayo Clinic in Minnesota, Dr. David Ahlquist of the Digestive
Diseases Conference in Chicago, said: They were 70 normal, DNA testing,
the results are all negative. Ahlquist said in a telephone interview:
"did not receive screening for cancer is deplorable, and a very high
mortality rate of these cancers, the study has opened the door to
detect cancer." "Pancreatic cancer The 5-year survival rate of only
about 5% or less. if you can not early detection of pancreatic cancer,
it is difficult to improve the survival rate. "In the United States,
gastrointestinal cancer-related deaths caused by cancer deaths account
for about 1 / 4, However, currently only on routine screening for colon
cancer.
All the gastrointestinal tract is a common feature of cancer cells
shed, and with the lower digestive tract with the feces excretion.
Stool samples are Ahlquist and his colleagues ongoing DNA testing
expanded edition of colon cancer. The detection method is to find
through the gastrointestinal tract when the stool samples with the
tumor or evidence of precancerous polyps in the cells. Ahlquist said:
"All the gastrointestinal tract is a common feature of cancer cells
shed, and with the lower digestive tract with the feces excretion. We
have this common biological characteristics as a screening tool."
Methods:
The team tested 70 suffering from a variety of digestive tract
cancers (including colon, larynx, esophagus, stomach, pancreas, bile
duct, gallbladder, small intestine) patients to confirm whether it can
be found in faecal samples from the abnormal gene. They also carried
out on 70 healthy people had stool samples testing.
Results:
The results of the method was found 65% of esophageal cancer, 62%
of pancreatic cancer and 75% of the bile duct and gallbladder. Also
found that 100% of gastric cancer and colorectal. The detection of
early cancer detection results with the same advanced cancer.
Development prospects:
Ahlquist said: "We are looking for specific DNA changes in cancer.
In this study proved that these DNA changes are very reliable marker."
Ahlquist said: "He and the Mayo Clinic in the stool DNA test on both
the economic interests, they want to be for this technology transfer to
companies to enable the detection of commercialization. "
