Hematuria alert the elderly renal cell carcinoma

Renal cancer is renal tubular epithelial cells derived from adenocarcinoma, 85% were clear cell carcinoma, there is a part of the granular cell carcinoma and mixed cell carcinoma. Cancer often have hemorrhage, necrosis, cystic change and calcification. Renal parenchyma was born and grew up after the invasion, oppression, destruction of renal pelvis and a crisp, to the renal capsule to external developments, the formation of blood vessel tumor emboli or transfer to the lymph nodes and other organs.

Most of the early asymptomatic until the tumor has grown large or invasive to the renal pelvis and calyceal within the abdominal mass and hematuria may occur.

1, urinary tract imaging: You can display a small cup of renal stretch deformation, distortion thinning, small lights destruction, or a small lamp expansion deformation. When the tumor volume significantly to the growth in all directions, the majority of renal minor calyx elongated, thinned, deformation, and sometimes into the renal pelvis, or upper ureter is also pushed down to the opposite side, even more than the center line, its shape resembling spider full sample, therefore called "Spider-foot sign."

2, B Ultra Performance: can be displayed within the renal parenchyma echo irregular border, internal echo clutter, ranging uneven level of the real mass. Shape deformation of the entire kidney, localized swelling protruding beyond the normal wild contour.

3, CT manifestations: renal scan shows local uplift, the internal low-density non-uniform, the spot seen in films or small point-like calcification, and sometimes was shell-like; enhanced scan after a normal part of the kidney increased significantly, while the cancer was enhanced compared with low degree of internal enhanced irregularity, there is more low-density necrotic area. Cancer can be pierced capsule into the perirenal fat layer, late perforation of renal fascia outside the organization spread to the kidneys. Multi-stage renal cell carcinoma with Robson stage approach, namely, stage ' cancer limited to the renal capsule; ' cancers had been pierced capsule, invasive fat layer, is still confined within the renal fascia; ' cancers have invaded renal vein or (and) the inferior vena cava, the local lymph node metastasis may be; ' cancers have been pierced renal fascia, or intrusion into adjacent organs or distant metastasis.

4, MR performance: in a multi-position observation to understand the scope of tumor invasion, slightly better than CT edge.

In general, the 50-year-old to 70-year-old is a high incidence of renal cell carcinoma of age, but these groups, it is highly vulnerable to misdiagnosis. Due to lack of awareness of self-identification, and many elderly patients will often hematuria, pain and other early symptoms of renal cell carcinoma mistaken for the normal performance of the natural weak until apparent when the thought of back pain treatment, after diagnosis of advanced cancer. Thus, frequent haematuria in the elderly need to be vigilant for early acceptance of kidney function tests to screen early stage renal tumors.

At present, for advanced and metastatic renal cell cancer treatment is mainly surgical combination of radiotherapy and chemotherapy, a number of multi-target drug therapies such as sunitinib are also constantly attempts. At the same time, renal cell carcinoma patients in regular follow-up is also very necessary, through the doctors can keep abreast of follow-up of patients with surgical complications, and kidney morphological changes, an appropriate extension of the survival rate of patients.

In addition, the elderly in order to reduce the risk of renal cell cancer risk, also need to pay special attention in their daily diet, stay away from smoking and drinking, eat high-salt high-sugar foods, while avoiding the food animal offal, as well as fresh seafood, and to ensure a daily a certain amount of drinking water.
  • Resources

  • Archive